欧美AV Professor鈥檚 Research Documents Medically Important Mosquitoes
Tue, 06/28/2022 - 09:26am | By: Ivonne Kawas
A research paper recently published by Dr. Don Yee鈥檚 lab in the School of Biological, Environmental and Earth Sciences (BEES) at 欧美AV (欧美AV) documents for the first time how many mosquitoes are medically important across the world.
The exact number of mosquito species relevant to human health is unknown, posing challenges in understanding the scope and breadth of vector鈥損athogen relationships, and how resilient mosquito vector鈥損athogen networks are to targeted eradication of vectors. Therefore, Dr. Yee and his students embarked on performing an extensive literature survey to document medically important mosquitoes in the paper titled: 鈥�Robust network stability of mosquitoes and human pathogens of medical importance.鈥�
鈥淭o date no scientific investigation has been made to count the mosquito species involved in the spread of human pathogens that cause disease,鈥� said Dr. Don Yee. 鈥淲e performed an extensive literature survey to determine the associations between mosquito species and their associated pathogens of human medical importance.鈥�
As Dr. Yee鈥檚 team performed this survey, for each vector鈥損athogen association, they determined the strength of the associations (i.e., natural infection, lab infection, lab dissemination, lab transmission, known vector). A network analysis was used to identify relationships among all pathogens and vectors. Finally, they examined how elimination of either random or targeted species affected the extinction of pathogens.
In their results they found that 88 of 3578 mosquito species (2.5%) are known vectors for 78 human disease-causing pathogens; however, an additional 243 species (6.8%) were identified as potential or likely vectors, bringing the total of all mosquitos implicated in human disease to 331 (9.3%). Network analysis revealed that known vectors and pathogens were compartmentalized, with the removal of six vectors being enough to break the network (i.e., cause a pathogen to have no vector). However, the presence of potential or likely vectors greatly increased redundancies in the network, requiring more than 41 vectors to be eliminated before breaking the network.
鈥淔or the first time we determined how many mosquito species are important for human health, and also the strength of associations between pathogens and mosquitoes,鈥� said Dr. Yee. 鈥淲e found that less than 10% of all mosquito species are important in human disease, however the associations between mosquitoes and pathogens are strong, making elimination of pathogens exceedingly difficult through just mosquito control. This work also suggests we still have a long way to go to fully understand all the mosquito species that are relevant to human health.鈥�
Parasites & Vectors is an open access, peer-reviewed online journal dealing with the biology of parasites, parasitic diseases, intermediate hosts, vectors and vector-borne pathogens.
To learn more about Dr. Yee and his research visit his 欧美AV faculty profile. To read this paper, visit the journal .